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Chapter 2: Understanding the Biosafety Cabinet

From the earliest laboratory-acquired typhoid infections to the hazards posed by today's antibiotic-resistant bacteria and rapidly mutating viruses, threats to worker safety have stimulated the development and refinement of cabinets in which infectious microorganisms and potentially harmful aerosols could be handled safely. There has also been increasing demand to protect work in progress from particulate contamination, especially in the areas of micro technologies.

Biological Safety Cabinets use High-Efficiency Particulate Air (HEPA) or Ultra-low Penetration Air (ULPA) filters in their Supply and Exhaust systems to provide safe particle free air. An air barrier at the front of the cabinet is created by an aerodynamic air foil and a large access opening to create a strong air barrier of 105 fpm (0.50 m/s). The HEPEX Zero Leak Airflow System helps create true laminar airflow by evenly distributing air through the supply filter creating true laminar airflow over the work surface and thereby minimizing cross contamination. Exhaust air passes through a HEPA filter before entering the laboratory and/or world environment.

In order for the Biological Safety Cabinet to do its job, laboratory personnel must be trained in the correct use and maintenance of biological safety cabinets, and follow the guidelines to ensure that personnel, product and environmental protection are maintained.

Biological Safety Cabinets were designed to remove or minimize exposures to hazardous biological materials and particulates. They are the principal device used to provide containment of infectious splashes or aerosols today.

Your NuAire Biological Safety Cabinet will meet your laboratory requirements for life science research, clinical or industrial applications. Each comes with NuAireā€™s legendary reputation for a commitment to quality and dependability, and backed by a level of customer service available only from NuAire.

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