The NuAire LabGard NU-581 is a Class II, Type A2 biosafety cabinet engineered for handling active pharmaceutical ingredients (APIs), powders, and cytotoxic compounds. It adds multi-stage HEPA filtration, including a wedge-shaped lower-stage prefilter array with bag-in/bag-out service, and is certified to NSF/ANSI 49, EN 12469, and DIN 12980. Download the brochure to see how it protects operators and preparations.

Enhanced Filtration for Pharmaceutical Powder Handling

Weighing and dispensing potent powders puts the operator closest to the hazard at the moment containment matters most. The NuAire LabGard NU-581 is a Class II, Type A2 biosafety cabinet built for that work — handling APIs, fine powders, and cytotoxic compounds with added HEPA filtration stages that capture particulate earlier in the airflow path. The brochure shows how that protection works, stage by stage.

What the NU-581 Brochure Covers

The two-page flyer is a quick, sharable overview for anyone evaluating containment for potent-compound work. Inside:

• How multi-stage HEPA filtration captures API and powder particulate earlier in the airflow path
• The wedge-shaped lower-stage HEPA prefilter array and its bag-in/bag-out safe-change service
• How the design supports safer, more controlled lower-filter maintenance
• The standards behind the cabinet: NSF/ANSI 49, EN 12469, and DIN 12980 — the reference for cytostatic and cytotoxic containment

Built for API Powders and Cytotoxics

What sets the NU-581 apart from a standard Class II, Type A2 cabinet is a dedicated lower-stage filtration layer: an array of wedge-shaped HEPA prefilters mounted under the work surface. They capture particulate earlier and can be isolated for bag-in/bag-out service, so routine filter changes do not become the weak point in your containment program. It suits pharmacists, formulation scientists, and safety officers working in pharmaceutical R&D, potency, and compounding where the primary hazard is airborne particulate. For volatile hazardous drugs or applications needing an externally vented control, review the primary engineering controls and non-sterile hazardous drug compounding pages before specifying.

Download the NU-581 Brochure

Download the LabGard NU-581 brochure for the full overview. Need complete specifications and configurations? See the NU-581 product page, or pull the model-specific 115 V and 230 V (E) purchase specifications. Ready to size a cabinet for your lab? Request a quote or talk to a NuAire specialist.

Frequently Asked Questions

What is the NuAire NU-581 biosafety cabinet used for?

The NuAire LabGard NU-581 is a Class II, Type A2 biosafety cabinet used for non-sterile handling of active pharmaceutical ingredients (APIs), fine powders, and cytotoxic compounds. Its multi-stage HEPA filtration and lower-stage wedge prefilter array suit pharmaceutical R&D, potency work, and compounding where the primary hazard is airborne particulate.

What standards does the NU-581 meet?

The NU-581 is certified to NSF/ANSI 49 (North American Class II biosafety cabinet standard), EN 12469 (European microbiological safety cabinet standard), and DIN 12980 (the standard for safety cabinets used with cytostatic and cytotoxic substances). DIN 12980 compliance is the reference that distinguishes cabinets intended for hazardous-drug and API powder handling.

How does the NU-581 differ from a standard Class II, Type A2 biosafety cabinet?

The NU-581 adds a dedicated lower-stage filtration layer a standard Type A2 cabinet does not have: an array of wedge-shaped HEPA prefilters under the work surface. These capture API and powder particulate earlier and can be isolated for bag-in/bag-out service, reducing potential exposure during filter replacement.

Is a Class II, Type A2 cabinet appropriate for hazardous drug compounding under USP 800?

A Class II, Type A2 cabinet provides personnel, product, and environmental protection and is appropriate for non-sterile handling of particulate hazardous drugs and APIs. USP 800 requires a containment primary engineering control (C-PEC), and for many sterile or volatile hazardous-drug applications an externally vented cabinet is preferred. Confirm your requirements on NuAire’s primary engineering controls resources and consult USP 800 before specifying.