Water Jacket CO2 Incubator

Water Jacket | 160-Liter Capacity | Oxygen Suppression | Temperature & CO2 Control

In-VitroCell CO2 Incubator model NU-8631 uses a water jacket, a heater, and temperature probes to control the temperature in the growth chamber. Model NU-8631 specializes in applications involving the need to maintain oxygen levels. Suppressed oxygen levels or hypoxic conditions in the growth chamber are controlled by monitoring O2 levels through a sensor and injecting nitrogen gas to meet the setpoint. Features such as an easy-to-use interface, top-notch filtration, and constant monitoring of chamber conditions give labs, both large and small, assurance that their samples will be protected. The NU-8631 is the perfect solution for stem cell and age-related research studies.

Request a Quote

A Product to Meet Your Need

Model NU-8631 is available in two electrical configurations.






Quick Specs

Air Cleanliness (ISO 14644) ISO-Class-5
CO2 Accuracy ± 0.1%
CO2 Recovery Up to 5% ± 0.2% / -0.5 in 5 minutes Average
Control System NuTouch
Temperature Accuracy °C ± 0.1%
Temperature Control Water Jacket
Temperature Recovery 0.12°C/min. on Average
Temperature Uniformity °C ± 0.20°C @ 37°C
  • Features
  • Specs
  • Options & Accessories
  • Resources
  • Citations
CO2 Incubator Oxygen Control for Hypoxic Studies

Hypoxic Conditions

Oxygen Control

For more sensitive cells lines prone to stress and DNA damage, CO2 Incubator models featuring Oxygen control utilize an O2 sensor to monitor oxygen in the growth chamber. Nitrogen (N2) gas is injected to suppress oxygen to set point. An extensive O2 range applies to various research applications, including the brain, eyes, liver, heart, kidneys, and more.


Optimal CO2 Levels

Infrared (IR) Sensor

A single source dual wave infrared (IR) sensor controls CO2 levels within the growth chamber to maintain an optimal PH. The wavelengths used are absorbed only by CO2, making the measurements insensitive to other components such as water vapor. Advanced design provides a stable output minimizing drift, and requires less frequent calibrations.

CO2 Incubator Water Jacket Temperature Control

Precise Uniformity

Water Jacket Temperature Control

In-VitroCell Water Jacket CO2 Incubators maintain accurate temperature with the large 18 gallons (68.1-liter) water jacket that surrounds the inner chamber. Heated water in this jacket circulates around the growth chamber, keeping the temperature uniform within the growth chamber ±0.2°C. Precise temperature control is aided by the R5 insulation that lines the outer chamber walls that minimize heat loss.

The door and perimeter heaters are microprocessor-controlled to adjust to the room's ambient temperature. They can also be adjusted manually from ±20 percent to reduce condensation within the growth chamber.

CO2 Incubator Coved Interior Corners

Easy to Clean, Minimize Contamination Risks

Coved Interior Corners

NuAire CO2 incubators are designed to minimize potential hiding places for contamination. Coved corners and a crevice-free interior, which makes it easy to clean.

The NuAire© Advantage

NuAire® utilizes an independent network of sales and service professionals offering our customers a vast array of knowledge and relationships. Our inside sales and service teams are the pride of the industry; some of which have been with NuAire® since the beginning in 1971. We work hard and diligently to make you happy. That is our mission, and that is why we come to work every day. Purchase a NuAire® and become part of our family.


Backed by the Industry's Best

  • 3 Years Parts & Labor, IR Sensor 5 Years Parts Only (United States and Canada)
  • Consult Local Distributor (Global)

Standard Features

  • Chamber Volume: 160L (5.65 Cu. Ft.)
  • NuTouch Electronic Control System
  • Decontamination Cycle: Not Available
  • Humidity Control: Water Pan, Convection
  • O2 Control: Sensor (0.5 - 21%)
  • Closed Loop HEPA Filtration System
  • Leg Levelers
Est. Shipping Width Inches (mm) 31 (787)
Est. Shipping Height Inches (mm) 49 (1245)
Est. Shipping Depth Inches (mm) 33 (838)
Access Port Location Right Side
Air Cleanliness (ISO 14644) ISO-Class-5
Chamber Air Circulation Method Air Pump
Chamber Air Filter 99.97% Efficiency @ ≥ 0.3 Micron Capsule Filter Located in Sensor Bay
Chamber Heater(s) Location Bottom of Chamber
Chamber Jacket Technology Water Jacket, 18 Gallon (68-Liter)
CO2 Accuracy ± 0.1%
CO2 Control Logic Fixed Algorithm/Manual, Environmental Adaptable
CO2 Display Resolution 0.1%
CO2 Range 0.1 to 20%, 5% Default Set Point
CO2 Recovery Up to 5% ± 0.2% / -0.5 in 5 minutes Average
CO2 Sensor Type Infrared (NDIR)
Control System NuTouch
Data Output Features RS-485, USB, 4-20mA
Door and Perimeter Heater Control Logic Base Duty Cycle set to chamber temperature Set-Point, Proportional 0-100% [manually adjustable
Electrical Configuration 115V60Hz, 230V5060Hz
Exterior Depth Inches (mm) 27 (685)
Exterior Door Seal Magnetic Outer Door Gasket
Exterior Height Inches (mm) 37.75 (958)
Exterior Material 16 Gauge Steel with Textured Polyurethane Finish
Exterior Width Inches (mm) 25.625 (649)
Footprint Depth inches (mm) 17.5 (445)
Footprint Width inches (mm) 22 (557)
In-line Gas Filters 99.97% Efficiency @ ≥ 0.3 Micron Disk Filters for Gas & Air Supplies, Disk Filter for CO2 Sensor
Segmented Doors Optional Set of 4 Inner Doors
Inner Doors One Standard, Sectional optional
Insulation Insulation with R5.0 Rating
Interior Depth Inches (mm) 20.625 (524)
Interior Door Seal Silicone Rubber Gasket
Interior Height Inches (mm) 24 (611)
Interior Material Polished Type 304L 16 Gauge Stainless Steel
Interior Volume Cubic Feet (Liters) 5.65 (160)
Interior Width Inches (mm) 20.375 (518)
Net Weight lbs (kg) 403 (183) includes full water jacket and shelves
O2 Accuracy ± 0.25%
O2 Control Logic Fixed algorithm/ manual environmental adaptable
O2 Display Resolution 0.1%
O2 Measuring Range 0 - 25%
O2 Set Point Range 0.5 -21.0% (ambient) (21.0% Default)
O2 Recovery 5.0 ± 0.5% twenty minutes on Average
O2 Sensor Type Zirconia Ceramic
Power Cord Length Foot (Meter) 8 (2.5)
Remote Alarm Terminals Standard
RH Accuracy Not available
RH Control Method Water Pan
RH Control Logic Not available
RH Control Range Not available
RH Display Resolution Not available
RH Evaporator Box Capacity Not available
RH Recovery Not available
RH Sensor Type Not available
RH Water Pan Capacity 2L (Recommended Fill 1.5L)
Sample Port Location Inner Glass Door
Shelf Capacity lbs (kg) 25 lbs per Shelf / 125 lbs per Incubator
Shelf Depth Inches (mm) 18 3/4 (476)
Shelf Material Stainless Steel or Copper Alloy
Shelf Width Inches (mm) 18 (457)
Shelves 4 Shelves Supplied, 16 Shelves Maximum Capacity
Est. Shipping Weight lbs (kg) 370 (168)
Decontamination Cycle Not available
Temperature Accuracy °C ± 0.1%
Temperature Control Water Jacket
Temperature Control Range 5°C above ambient (to a 30°C max ambient) to 55°C
Temperature Display Resolution 0.1°C
Temperature Recovery 0.12°C/min. on Average
Temperature Sensor Type Precision Integrated Circuit
Temperature Set-Point Range 5°C to 55°C (37.0°C Default)
Temperature Uniformity °C ± 0.20°C @ 37°C
Water Pan Depth 1.5 (38)
Water Pan Length Inches (mm) 12 (305)
Water Pan Width 10 (254)


NU-8631 NU-8631E
Electrical Configuration 115V60Hz 230V5060Hz


NU-8631 NU-8631E
Safety Certification [ "", "UL, UL-C" ] [ "", "UL, UL-C" ]

Built-in Options

Humidity Display Single Unit


With Cooling Coil
Without Cooling Coil

Inner Door

Sectioned Inner Door
Standard Glass Inner Door

Outer Door (Right Hinge Standard)

Left Side Door Hinge

Packing Option

Packaging 2 Incubator Stacked with NU-8653
Packaging Single Incubator

Power Cord

Euro Power Cord Option Shipping Kit
UK Power Cord Option

NuAire Accessories

Please keep in mind parts and accessories are product and size specific, contact your sales representative for any clarity to your size questions.
Warranty NuAire Standard CO2 Incubator Warranty in United States and Canada

CO2 Incubator Standard Warranty for US and CA

View the warranty
White Paper CO2 Incubator Buying Guide

CO2 Incubator Buying Guide

Learn More
BIM Revit

NU-8600 Family of Water Jacket CO2 Incubators 3D Model

Learn More
Manuals OM0245 CO2 Incubator Manual for models NU-5810, NU-5820, NU-5831, and NU-5841

OM0246 CO2 Incubator Manual for NU-5810/E through NU-5841/E

Read the manual
Manuals OM0253 NU-8600/E through NU-8631/E CO2 Incubator Manual

OM0253 NU-8600/E through NU-8631/E CO2 Incubator Manual

Read the manual
Manuals Operation and maintenance manual for NU-5800 and NU-5800E Series 12 CO2 Incubator

OM0245 NU-5800 and NU-5800E Series 12 CO2 Incubator Manual

Read the manual
Brochure In-VitroCell CO2 Incubator Brochure

In-VitroCell CO2 Incubator Brochure

Download the brochure



How it works. NuAire sells through a network of knowledge representatives, some who have been selling and servicing NuAire since our inception in 1971. We’ll notify your local representative who will reach out to you. He/She can assist with product selection/configuration, training, installation guidance, support throughout the life of the product, or just provide you pricing in a quick manner. We have some of the best customers who are doing some groundbreaking work. We would love for you to join our family and experience the NuAire Advantage.

Why Your Colleagues Choose NuAire

Let me say that we have come to rely on Nuaire, as a strong partner to Vaccines & it is so because of our valued relationship with George Riley, who is always at our beck and call. God bless him (Keep him for Sure!!) & your Quality BioSafety Cabinets. Service is King & Quality is his side-kick!! So thank you! We look forward to a long and prosperous relationship. Keep up the good work & quality build.

Operations Manager at a Large Pharmaceutical Company

Cookies help us improve your website experience.
By using our website, you agree to our use of cookies.